For chronic weight management in adult patients with a BMI ≥30 kg/m2, or ≥27 kg/m2 with one or more weight-related comorbidities, as an adjunct to a reduced-calorie diet and increased physical activity. Click for Limitations of Use.
Frequently Asked Questions
Get the answers you need to help set patients up for weight-loss success
As you consider prescribing Saxenda® for your patients, you may have some questions. Below you will find answers that will help you treat effectively and communicate pertinent information to your patients and staff.
You can also call 1-877-304-6894 anytime with questions about Saxenda®.
Saxenda® (liraglutide) injection 3 mg is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (eg, hypertension, type 2 diabetes mellitus, or dyslipidemia).
GLP-1 is a native hormone that is released in response to food intake and acts as a physiological regulator of appetite.1,2 97% similar to native GLP-1, Saxenda® works in the braina to increase feelings of satiety and decrease hunger and thereby reduce food intake, leading to weight loss.1,3
aShown in animal models.
The most common side effects, reported in ≥5% are: nausea, hypoglycemia, diarrhea, constipation, vomiting, headache, decreased appetite, dyspepsia, fatigue, dizziness, abdominal pain, and increased lipase.1
Nausea is the most common side effect when first starting Saxenda®, but tends to decrease over time as your patient’s body gets used to treatment.1
Adherence to the dosing schedule should help reduce the likelihood of gastrointestinal symptoms.1
Once you’ve verified that your patient is covered and the prior authorization (PA) is approved, you can prescribe Saxenda® through your electronic health record (EHR) system. In some states, a separate prescription may be required for the NovoFine® 32G Tip needles.
When you prescribe, you can also provide your patient with a Saxenda® Sample Kit to help them get started right away.
- Patients should follow a 4-week dose escalation in order to reach the clinically efficacious 3-mg dose, which reduces the likelihood of gastrointestinal symptoms1
- The Saxenda® starting dose is 0.6 mg per day for 1 week1
- Patients increase the dose by 0.6 mg each week until the full maintenance dose of 3 mg is reached1
Nausea is the most common side effect when first starting Saxenda®, but decreases over time for most people as their body gets used to treatment.1 If a patient experiences nausea, you may consider advising them to4:
- Eat bland, low-fat foods, like crackers, toast, and rice
- Eat foods that contain water, like soups and gelatin
- Avoid lying down after they eat
- Go outdoors for fresh air
Remember to reinforce adherence to the dosing schedule, which is designed to reduce the likelihood of gastrointestinal symptoms.1
If patients cannot tolerate an increased dose during dose escalation, consider delaying escalation for approximately 1 week. If a patient cannot tolerate the 3-mg dose, discontinue treatment.1
Instruct patients to store new, unused Saxenda® pens in the refrigerator between 36°F and 46°F (2°C to 8°C). Once a patient is actively using the pen, it can be stored at room temperature (59°F to 86°F; 15°C to 30°C) or in a refrigerator for 30 days.1
Refer patients to the full Prescribing Information for more details regarding injection and pen storage.
Consider administering the first injection of Saxenda® in-office to reduce the risk of administration errors.
Patients will inject their dose of Saxenda® under the skin in the stomach area (abdomen), upper leg (thigh), or upper arm daily. Indicate each of the 3 appropriate injection areas when prescribing Saxenda® and ensure that patients understand that they should never inject into a vein or muscle.1
Refer patients to the Instructions for Use in the full Prescribing Information for full usage instructions.
Our step-by-step video will guide you through the Saxenda® injection technique.
Refer patients to the Instructions for Use in the Prescribing Information for more information regarding proper injection, storage, and handling techniques.
PATIENT SUPPORT & SAVINGS
Some patients can reduce the cost of their Saxenda® prescription by activating a Saxenda® Savings Card. Eligible patients may pay as little as $25 or save up to $200 per prescription when using the Saxenda® Savings Card.a
Be sure to direct your patients to Saxenda.com to activate their Saxenda® Savings Card before they pick up their prescription at the pharmacy.
Patients can estimate how their insurance coverage will impact the price of Saxenda® by using our Co-Pay Calculator.
aEligibility and other restrictions apply. Novo Nordisk reserves the right to modify or cancel this program at any time.
Consider scheduling the first follow-up visit with your patient between 2 and 8 weeks to evaluate initial progress and monitor for side effects. Remain an active part of their treatment journey by following up regularly and encouraging them to reach out to you or your staff with any questions along the way.
Remember to follow up with patients at 16 weeks to evaluate change in body weight, especially if a PA reauthorization is necessary to ensure treatment coverage. If a patient has not lost at least 4% of baseline body weight, it is unlikely they will achieve and sustain clinically meaningful weight loss with continued treatment. In this case, Saxenda® should be discontinued.
Looking for help with implementing a follow-up protocol for Saxenda®?
Yes! SaxendaCare® is a complimentary support platform designed to work with Saxenda® using scientifically proven weight-loss and maintenance strategies. SaxendaCare® supports patients with features including a SaxendaCare® Welcome Kit, live phone or in-app messaging support, and helpful reminders regarding their prescription and personal goals.
When enrolled in SaxendaCare®, patients can choose the coaching option that works for them; live phone calls with SaxendaCare® coaches, or in-app messaging support powered by Noom.
Patients are automatically enrolled in SaxendaCare® when they activate their Saxenda Savings® Card. They may also enroll anytime at SaxendaCare.com.
Yes! Novo Nordisk has a helpful tool that you can print and fill out with your patient at their visit. Use our Weight Management Plan to guide them in identifying areas of focus and setting realistic expectations for their long-term success.